Why the study?
Does exercise training improve oxygen consumption and exercise duration in a patient with congestive heart failure on continuous dobutamine?
Does exercise training improve oxygen consumption and exercise duration in a patient with congestive heart failure on continuous dobutamine?
Exercise training may improve functional capacity in patients with severe heart failure dependent on continuous inotropic support, potentially facilitating weaning from inotropes.
May support exercise training in dobutamine-dependent HF; hypothesis-generating and requires confirmation in controlled trials.
We present a 53-yr-old man with congestive heart failure who underwent 32 wk of exercise training. The patient was on a continuous infusion of dobutamine for 10 months prior to exercise training, which was subsequently discontinued at wk 24 of exercise training. Symptom-limited graded exercise tests were performed at baseline, wk 12, wk 24, and wk 32 of exercise training. While on a continuous infusion of dobutamine, the patient's oxygen consumption and exercise duration were increased during the exercise training period. Additionally, the patient was able to maintain these changes for 8 wk while continuing to exercise after the discontinuation of the dobutamine therapy.
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Kataoka et al. (1994) studied this question.
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