Key result
PLAATO implantation in high-risk atrial fibrillation patients resulted in an observed stroke risk of 3% per year over 36 months, compared to a predicted risk of 8.6% per year.
Why the study?
Does percutaneous left atrial appendage transcatheter occlusion (PLAATO) prevent stroke in patients with atrial fibrillation and contraindications to anticoagulation?
Population
11 patients with atrial fibrillation and contraindications to anticoagulation, with at least one risk factor…
Design
Cohort
Follow-up
36 +/- 1.4 months
Authors
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May support stroke prevention with PLAATO in anticoagulation-ineligible AF; leaves open need for randomized confirmation.
Cohort (n=11)
No
Does percutaneous left atrial appendage transcatheter occlusion (PLAATO) prevent stroke in patients with atrial fibrillation and contraindications to anticoagulation?
Absolute Event Rate: 3% vs 8.6%
PLAATO implantation may safely reduce the risk of stroke in high-risk AF patients with contraindications to anticoagulation over long-term follow-up.
El‐Chami et al. (2007) conducted a cohort in Atrial fibrillation (n=11). Percutaneous left atrial appendage transcatheter occlusion system (PLAATO) vs. Predicted stroke risk (CHADS2 score) was evaluated on Incidence of stroke. PLAATO implantation in high-risk atrial fibrillation patients resulted in an observed stroke risk of 3% per year over 36 months, compared to a predicted risk of 8.6% per year.
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