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October 26, 2016Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical PsychopharmacologyOpen Access

Autopsy findings in three cases of sudden death suggest that long-term antipsychotic use may cause fatal eosinophilic myocarditis due to a hypersensitivity reaction.

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Population

n=3 cases of sudden death in patients receiving long-term drug treatment for schizoaffective disorder

Design

Case_series

Key result

Autopsy findings in three cases of sudden death suggest that long-term antipsychotic use may cause fatal eosinophilic myocarditis due to a hypersensitivity reaction.

Authors

AŞAhmet ŞahpazSPSultan PehlivanDTDilhan Türkkan

Discussion

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Member takes

Overview

Should not yet change practice; hypothesis-generating for antipsychotic-related fatal myocarditis.

Study Design

Type

Case Report (n=3)

Multicenter

No

Structured PICO

P
Population
3 patients with schizoaffective disorder who faced sudden death after long-term antipsychotic treatment.
E
Exposure
Long-term antipsychotic drug use
O
Outcome
Autopsy findings of eosinophilic myocarditissafety

Long-term antipsychotic use may cause fatal eosinophilic myocarditis as a hypersensitivity reaction, highlighting the need for clinical vigilance.

Cite This Study

Şahpaz et al. (2016) conducted a case report in Eosinophilic myocarditis (n=3). Long-term antipsychotic use was evaluated on Autopsy findings of eosinophilic myocarditis. Autopsy findings in three cases of sudden death suggest that long-term antipsychotic use may cause fatal eosinophilic myocarditis due to a hypersensitivity reaction.

synapsesocial.com/papers/6a787cba6789de8d0af7ceadhttps://doi.org/10.5455/bcp.20160502090929
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Eosinophilic myocarditis in an adolescent: a case report and review of the literature2012 · 16 citations
  2. 2A case report of eosinophilic myocarditis and a review of the relevant literature2015 · 43 citations
  3. 3Eosinophilic myocarditis: two case reports and review of the literature2013 · 30 citations
  4. 4Eosinophilic Myocarditis: From Bench to Bedside2024 · 18 citations
  5. 5Eosinophilic Myocarditis: A Diagnostic Challenge and Treatment Dilemma - A Case Report2024 · 1 citations