Population
Dictyostelium cell line
Comparison
Mutation designated my delta C34 in the myosin… vs Wild-type cells, null cells, and hmm cells
Design
Preclinical
Authors
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Does not support myosin C-terminus targeting in cardiac disease; leaves open its role in mammalian cytokinesis and development.
The 34-kDa carboxyl terminus of myosin is not required for the developmental cycle of Dictyostelium, although it is necessary for cytokinesis.
O'Halloran et al. (1990) studied this question.
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