Why the study?
Does losartan improve haemodynamics and is it well tolerated in heart failure models and patients?
Population
Animal models of heart failure and patients with heart failure
Design
Review
Authors
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May support losartan evaluation in heart failure; leaves open guideline integration pending randomized outcome trials.
Does losartan improve haemodynamics and is it well tolerated in heart failure models and patients?
Losartan provides haemodynamic benefits and is well tolerated in heart failure, supporting its potential clinical utility.
Sweet et al. (1994) studied this question.
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