Key result
Sugammadex compared to neostigmine resulted in no postoperative respiratory events in either group, though an unspecified PACU measurement was slightly higher.
Why the study?
Does sugammadex prevent postoperative respiratory events compared to neostigmine in patients undergoing laparoscopic sleeve gastrectomy?
Does sugammadex prevent postoperative respiratory events compared to neostigmine in patients undergoing laparoscopic sleeve gastrectomy?
In patients undergoing laparoscopic sleeve gastrectomy, the choice between sugammadex and neostigmine for neuromuscular reversal showed minimal clinical difference in respiratory outcomes, though neostigmine was associated with slightly lower PACU oxygen saturation.
Answers are grounded in this paper and cite their sources.
Observed respiratory differences after reversal should not change practice; hypothesis-generating for reversal agent trials.
was to find out if there was an association between the type of muscle relaxant reversal agent and the development of postoperative respiratory events in patients undergoing laparoscopic sleeve gastrectomy surgery. METHODS: in PACU, train-of four counts (TOF) before reversal, unexpected ICU admissions, duration of hospitalization and incidence of reintubation were recorded. RESULTS: was significantly lower in the PACU in the neostigmine group: 93% vs. 94% (p = 0.01). Respiratory rates were not different. After the administration of reversal, both groups had TOF counts of 4 with no fade assessed visually. There were no postoperative respiratory events or complications. The lack of difference in the other measured variables may stem from the small number of patients studied (pilot).
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Evron et al. (2017) studied Laparoscopic sleeve gastrectomy. Sugammadex vs. Neostigmine was evaluated on Postoperative respiratory events. Sugammadex compared to neostigmine resulted in no postoperative respiratory events in either group, though an unspecified PACU measurement was slightly higher.
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