Why the study?
Does pacing-induced left bundle branch block via atrioventricular sequential pacing impair left ventricular systolic and diastolic performance compared to right atrial pacing in patients with normal baseline conduction?
Does pacing-induced left bundle branch block via atrioventricular sequential pacing impair left ventricular systolic and diastolic performance compared to right atrial pacing in patients with normal baseline conduction?
Pacing-induced left bundle branch block acutely impairs both left ventricular systolic and diastolic performance, likely due to asynchronous contraction and relaxation.
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May warrant avoiding unnecessary AV sequential pacing in normal conduction; leaves open long-term outcome effects of induced dyssynchrony.
Tanabe et al. (1990) studied this question.
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