Why the study?
Does initial treatment with vitamin K antagonists improve hemodynamics and symptoms compared to surgery or thrombolysis in patients with bioprosthetic valve thrombosis?
Does initial treatment with vitamin K antagonists improve hemodynamics and symptoms compared to surgery or thrombolysis in patients with bioprosthetic valve thrombosis?
Vitamin K antagonist therapy provides similar hemodynamic and clinical improvement to surgery or thrombolysis for bioprosthetic valve thrombosis, suggesting it could be considered as first-line therapy in hemodynamically stable patients.
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VKA may warrant consideration in stable bioprosthetic valve thrombosis; hypothesis-generating and requires prospective confirmation before practice change.
Pislaru et al. (2014) studied this question.
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