Population
Chloralose-anesthetized cats (including vagotomized, sinoaortic-denervated, and intact nerve models)
Comparison
Epicardial or intracoronary administration of… vs Different states of nerve intactness
Design
Preclinical
Authors
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Cardiac sympathetic afferents may drive sympathetic excitation in disease; leaves open net effects and human relevance.
Cardiac sympathetic afferent neurons can exert significant excitatory influences on the cardiovascular system, even when opposed by inhibitory reflexes.
Reimann et al. (1980) studied this question.
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