April 1, 1981AJP Heart and Circulatory Physiology

Contrasting reflex influences of cardiac afferent nerves during coronary occlusion

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Population

Anesthetized cats in which sympathetic and/or vagal cardiac afferent nerves remained intact and arterial…

Design

Preclinical

Authors

LWLynne C. WeaverWestern University LDL. M. Danos ROR. S. OehlPrinceton University

Discussion

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Implication

Hypothesis-generating for cardiac afferent modulation of renal nerves in ischemia; leaves open translation to human therapies.

Structured PICO

Population

Anesthetized cats in which sympathetic and/or vagal cardiac afferent nerves remained intact and arterial baroreceptors remained intact or had been denervated

Intervention

Stimulation of cardiac sympathetic and vagal afferent nerves by occlusion of coronary arteries

Outcome

Changes in renal sympathetic nerve activity and systemic arterial blood pressuresurrogate

Cardiac sympathetic afferent nerves contribute significantly to cardiovascular control during myocardial ischemia by modulating renal nerve activity and blood pressure.

Cite This Study

Weaver et al. (1981) studied this question.

synapsesocial.com/papers/6a79b2e802ab7a73dd02800a https://doi.org/10.1152/ajpheart.1981.240.4.h620

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Contrasting reflex influences of cardiac afferent nerves during coronary occlusion

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Contrasting reflex influences of cardiac afferent nerves during coronary occlusion

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider