Key result
Aerobic exercise training prevented perivascular adipose tissue-induced alterations in thoracic aorta vascular reactivity and reduced iNOS protein expression in rats fed a high-fat diet.
Why the study?
Does aerobic exercise training improve perivascular adipose tissue function in the thoracic aorta of rats fed a high-fat diet?
Population
Male Wistar rats fed a high-fat diet or standard diet
Comparison
Aerobic exercise training vs Sedentary lifestyle (no exercise training)
Design
Preclinical
Authors
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Aerobic training partially restores PVAT anti-contractile function in obese rats; leaves open human translation and clinical relevance.
Does aerobic exercise training improve perivascular adipose tissue function in the thoracic aorta of rats fed a high-fat diet?
Aerobic exercise training prevents high-fat diet-induced alterations in perivascular adipose tissue function and vascular reactivity in the thoracic aorta of rats.
Araújo et al. (2017) studied High-fat diet-induced vascular alterations. Aerobic exercise training vs. Sedentary condition was evaluated on Vascular reactivity in thoracic aorta and iNOS protein expression. Aerobic exercise training prevented perivascular adipose tissue-induced alterations in thoracic aorta vascular reactivity and reduced iNOS protein expression in rats fed a high-fat diet.
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