August 1, 1989Hypertension

Caffeine may potentiate adrenocortical stress responses in hypertension-prone men.

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Why the study?

Does caffeine administration increase blood pressure and cortisol responses to stress in men at high risk for hypertension?

Structured PICO

Does caffeine administration increase blood pressure and cortisol responses to stress in men at high risk for hypertension?

Population

34 healthy men ages 21-35 years, stratified into high risk for hypertension (n=17, positive parental history and screening BP 135/85-155/95 mm Hg) and low risk (n=17, negative parental history and BP ≤132/84 mm Hg).

Intervention

Caffeine (3.3 mg/kg in grapefruit juice) administered orally before a psychomotor task.

Comparator

Oral placebo (grapefruit juice).

Outcome

Blood cortisol levels and blood pressures during rest and in response to a challenging psychomotor task.surrogate

Caffeine combined with mental stress potentiates blood pressure and adrenocortical responses in young men at high risk for hypertension.

Discussion

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Implication

Caffeine may amplify acute BP and cortisol reactivity to stress in high-risk men; hypothesis-generating for hypertension prevention trials.

Cite This Study

Lovallo et al. (1989) studied this question.

synapsesocial.com/papers/6a79d87afb5b6b43000dd313 https://doi.org/10.1161/01.hyp.14.2.170

Topics

Hypertension management

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Implication

Caffeine may amplify acute BP and cortisol reactivity to stress in high-risk men; hypothesis-generating for hypertension prevention trials.

Caffeine may potentiate adrenocortical stress responses in hypertension-prone men.

Structured PICO

Discussion

Implication

Cite This Study

Topics

Caffeine may potentiate adrenocortical stress responses in hypertension-prone men.

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider