Key result
The combination of exam stress and caffeine caused additive increases in blood pressure (+9/5 mm Hg in low-risk and +10/6 mm Hg in high-risk men; P<0.05).
Why the study?
Does caffeine consumption combined with stress increase blood pressure and cortisol secretion in male medical students at risk for hypertension?
RCT (n=31)
Double-blind
randomized
Does caffeine consumption combined with stress increase blood pressure and cortisol secretion in male medical students at risk for hypertension?
p-value: p=< .05
The combination of caffeine and mental stress produces additive increases in blood pressure, pushing nearly half of high-risk individuals into hypertensive ranges during high-stress periods.
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Caffeine may warrant restriction during work stress for hypertension-prone patients; extends additive BP effects to high- versus low-risk groups in RCT.
Shepard et al. (2000) conducted an RCT in Risk for hypertension (n=31). Caffeine vs. Without caffeine was evaluated on Cortisol levels and ambulatory blood pressure (p=< .05). The combination of exam stress and caffeine caused additive increases in blood pressure (+9/5 mm Hg in low-risk and +10/6 mm Hg in high-risk men; P<0.05).