Population
Bovine diaphragm sarcoplasmic reticulum fractions enriched in terminal cisternae
Design
Preclinical
Authors
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Should not yet inform clinical RyR targeting; extends isoform 3 characterization in animal models, leaving human relevance open.
The study establishes a methodology to isolate and characterize the low-abundance mammalian ryanodine receptor isoform 3, revealing its channel properties and first 2D structure.
Jeyakumar et al. (1998) studied this question.
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