Key result
Progression of carotid artery stenosis was associated with higher plasma urea (51.6 vs 43.0 mg/dl; p=0.013) and fibrinogen (493.2 vs 441.3 mg/dl; p=0.018), but lower BMI (24.6 vs 26.4; p=0.02).
Cohort (n=210)
No
Elevated plasma urea and fibrinogen, along with lower BMI, are associated with the progression of carotid artery stenosis, highlighting the role of metabolic and inflammatory factors.
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Hypothesis-generating for carotid stenosis progression; prospective validation required before any clinical application.
Batagini et al. (2015) conducted a cohort in carotid artery stenosis (n=210). Metabolic and inflammatory factors (plasma urea, fibrinogen, BMI) vs. Patients without progression of carotid stenosis was evaluated on Progression of carotid stenosis. Progression of carotid artery stenosis was associated with higher plasma urea (51.6 vs 43.0 mg/dl; p=0.013) and fibrinogen (493.2 vs 441.3 mg/dl; p=0.018), but lower BMI (24.6 vs 26.4; p=0.02).
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