Key result
The VALID-CRT risk score reliably predicted long-term total mortality, with patients in the highest risk quintile facing an 8-fold higher risk of death compared to the lowest quintile (HR 8.03; P<0.001).
Cohort (n=5,153)
Yes
Hazard Ratio: 8.03
Absolute Event Rate: 58.8% vs 10.3%
p-value: p=<0.001
The VALID-CRT risk score, using readily available clinical variables, reliably predicts long-term total and cardiovascular mortality in patients undergoing CRT.
No takes yet. Share an insight, caveat, or question.
Supports VALID-CRT for mortality risk stratification in CRT; prospective trials needed before changing practice.
Gasparini et al. (2015) conducted a cohort in Patients implanted with cardiac resynchronization therapy (CRT) (n=5,153). VALID-CRT risk score (highest quintile) vs. Lowest quintile of the VALID-CRT risk score was evaluated on Total mortality (HR 8.03, p=<0.001). The VALID-CRT risk score reliably predicted long-term total mortality, with patients in the highest risk quintile facing an 8-fold higher risk of death compared to the lowest quintile (HR 8.03; P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: