Key result
A 7-variable clinical risk score demonstrated modest discrimination (C statistic 0.71) for predicting 3-year mortality in patients implanted with a CRT-D.
Why the study?
Despite the established benefits of CRT-D in patients with heart failure, low LVEF, and wide QRS, mortality remains high in some patients.
Does a risk score based on 7 clinical variables predict early mortality at 3 years in patients implanted with a CRT-D?
Cohort (n=1,282)
Yes
Does a risk score based on 7 clinical variables predict early mortality at 3 years in patients implanted with a CRT-D?
Effect estimate: C statistic 0.71
May identify high-risk CRT-D recipients for closer monitoring; leaves open prospective validation and outcome impact.
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Theuns et al. (2019) conducted a cohort in Heart failure with CRT-D implantation (n=1,282). 7-variable clinical risk score was evaluated on mortality at 3 years (C statistic 0.71). A 7-variable clinical risk score demonstrated modest discrimination (C statistic 0.71) for predicting 3-year mortality in patients implanted with a CRT-D.
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