Why the study?
Does the addition of N2O, halothane, or enflurane attenuate the cardiovascular intubation response in normotensive otolaryngological patients?
Population
75 normotensive, otolaryngological patients (with an additional 25 patients in preliminary experiments)
Comparison
2 min artificial ventilation with 70% nitrous… vs 2 min artificial ventilation with 100% oxygen
Design
Other
Follow-up
Immediate (post-intubation)
Authors
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Should not yet change intubation protocols; leaves open efficacy of these agents versus modern alternatives in broader populations.
Does the addition of N2O, halothane, or enflurane attenuate the cardiovascular intubation response in normotensive otolaryngological patients?
The combination of halothane 2% with N2O effectively attenuates the cardiovascular response to intubation without causing significant arrhythmias.
Kautto et al. (1983) studied this question.
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