Key result
Administration of fish oil, gemfibrozil, and antum reduced serum triglyceride levels to ≤200 mg/dl in a pregnant woman with hyperlipidemic pancreatitis, although intrauterine fetal death occurred.
Case Report (n=1)
Hyperlipidemic pancreatitis during pregnancy carries a high risk of fetal mortality and requires immediate intervention to control triglyceride levels.
May support triglyceride-lowering exploration in pregnant pancreatitis; leaves open fetal safety and should not change practice.
Background & aim: Elevated triglyceride levels in women with hereditary forms of hypertriglyceridemia may involve the risk of pancreatic attacks during pregnancy. Case report:In this study, we present the clinical course of a 42-year-old pregnant woman with two vaginal deliveries and one cesarean section (gravidity: 4, parity: 3, live: 2, death: 1) admitted to our hospital. Gestational age was 33-34 weeks based on the last menstrual period and ultrasound results. Although hypertriglyceridemia and pancreatitis were controlled by pancreatitis treatment, intrauterine fetal death occurred in the patient. In addition, fish oil, gemfibrozil and antum were administered to decrease serum triglyceride (TG) levels. Finally, the patient was discharged with good general conditions and a TG level of ≤200 mg/dl four weeks after the onset of the disease. Conclusion: Hyperlipidemic pancreatitis is associated with maternal and fetal mortality and morbidity. Therefore, treatments should be initiated immediately after the diagnosis of this disease during pregnancy. Complications caused by elevated TG levels could be prevented with appropriate and timely interventions.
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Lotfalizadeh et al. (2015) conducted a case report in Hypertriglyceridemic Pancreatitis in Pregnancy (n=1). Pancreatitis treatment including fish oil, gemfibrozil, and antum was evaluated on Maternal and fetal outcomes and serum triglyceride levels. Administration of fish oil, gemfibrozil, and antum reduced serum triglyceride levels to ≤200 mg/dl in a pregnant woman with hyperlipidemic pancreatitis, although intrauterine fetal death occurred.
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