Why the study?
Does ouabain co-infusion affect blood flow responses to endothelium-dependent and independent vasodilators in healthy male volunteers?
Population
6 healthy male volunteers
Comparison
Ouabain co-infused with carbachol, bradykinin… vs Carbachol, bradykinin, and sodium nitroprusside…
Design
Other
Authors
Loading...
May reduce basal forearm blood flow without affecting vasodilator responses in healthy volunteers; leaves open relevance to disease states.
Does ouabain co-infusion affect blood flow responses to endothelium-dependent and independent vasodilators in healthy male volunteers?
In vivo, ouabain reduces basal forearm blood flow but does not affect endothelium-dependent or independent vasodilation, contrasting with previous in vitro findings.
Woolfson et al. (1991) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: