Population
Isolated plasma high-density lipoproteins and homogeneous preparations of spherical reconstituted HDL
Comparison
Variation in HDL core lipid composition and… vs HDL particles of different sizes and core lipid…
Design
Preclinical
Authors
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HDL size and core lipids may alter apo A-I function; leaves open effects on reverse cholesterol transport in humans.
Core lipid composition and particle size significantly alter the structural conformation of specific domains of apolipoprotein A-I on HDL, suggesting direct contact between central/C-terminal domains and core lipids.
Curtiss et al. (2000) studied this question.
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