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January 1, 1998Cardiovascular ResearchOpen Access

Effects of norepinephrine on expression of IGF-1/IGF-1R and SERCA2 in rat heart

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Authors

XSXiwu SunTaichung City Government YNYuk-Chow NgPennsylvania State University

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Implication

May inform NE-driven hypertrophy mechanisms in rodents; leaves open relevance to human HF gene regulation.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Sun et al. (1998) studied this question.

synapsesocial.com/papers/6a7a69964c448619ca0e2556 https://doi.org/10.1016/s0008-6363(97)00210-1

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Isoproterenol infusion induces alterations in expression of hypertrophy-associated genes in rat heart1995 · 142 citations
2Upregulation of IGF<sub>1</sub>, IGF<sub>1</sub>‐receptor, and late growth related genes in ventricular myocytes acutely after infarction in rats1994 · 77 citations
3Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium.1993 · 482 citations
4Messenger RNA expression and immunological quantification of phospholamban and SR-Ca2+-ATPase in failing and nonfailing human hearts2000 · 178 citations
5Regulation of myocardial Ca2+-ATPase and phospholamban mRNA expression in response to pressure overload and thyroid hormone.1989 · 289 citations