Why the study?
How do isoproterenol, l-norepinephrine, and intra-aortic counterpulsation affect systemic hemodynamics and myocardial metabolism in patients with shock due to acute myocardial infarction?
Population
21 patients in shock due to acute myocardial infarction
Comparison
Isoproterenol, l-norepinephrine, or intra-aortic… vs Baseline (before treatment)
Design
Case_series
Authors
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May support norepinephrine over isoproterenol in AMI shock; leaves open randomized confirmation.
How do isoproterenol, l-norepinephrine, and intra-aortic counterpulsation affect systemic hemodynamics and myocardial metabolism in patients with shock due to acute myocardial infarction?
In cardiogenic shock complicating acute myocardial infarction, l-norepinephrine and intra-aortic counterpulsation improve myocardial perfusion and metabolism compared to isoproterenol, supporting the use of norepinephrine as the initial vasoactive agent of choice.
Mueller et al. (1972) studied this question.
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