Why the study?
Does reducing the furosemide dose to one-third of the stabilization dose maintain clinical and haemodynamic stability in patients with advanced congestive heart failure?
Population
29 patients with advanced congestive heart failure stabilized on standard medical treatment for at least 3…
Comparison
Reduction of daily furosemide dose to 1/3 of the… vs Baseline clinical and haemodynamic status prior…
Design
Cohort
Follow-up
2 months
Authors
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May support short-term stability after furosemide reduction in advanced HF; leaves open randomized confirmation before practice change.
Does reducing the furosemide dose to one-third of the stabilization dose maintain clinical and haemodynamic stability in patients with advanced congestive heart failure?
In patients with advanced heart failure stabilized on medical therapy, reducing the furosemide dose by two-thirds is safe and well-tolerated in the majority of patients, with clinical deterioration being fully reversible upon dose resumption.
Alexopoulos et al. (2003) studied this question.
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