Key result
Left atrial appendage occlusion is discussed as a strategy to eliminate the need for warfarin in patients with atrial fibrillation to prevent stroke, which has an incidence of 780,000 cases yearly.
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LAAO discussion for warfarin avoidance in AF is hypothesis-generating; leaves open efficacy confirmation versus anticoagulation in randomized trials.
Holmes et al. (2009) conducted an editorial in Atrial fibrillation and stroke. Left Atrial Appendage Occlusion vs. Warfarin was evaluated. Left atrial appendage occlusion is discussed as a strategy to eliminate the need for warfarin in patients with atrial fibrillation to prevent stroke, which has an incidence of 780,000 cases yearly.
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