Key result
Exposure to an elevation of 1,600 meters resulted in progressive right-sided heart failure and right ventricular hypertrophy in 55 Holstein heifers, consistent with brisket disease.
Population
55 Holstein heifers with progressive right-sided heart failure at a heifer-raising facility and 2 dairies on…
Design
Case_series
Follow-up
5 years (2007-2011)
Authors
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May warrant monitoring Holstein heifers at 1,600 m; leaves open generalizability to other breeds or lower altitudes.
Observational (n=55)
Yes
Progressive right-sided heart failure (brisket disease) due to pulmonary hypertension can occur in Holstein heifers at a modest elevation of 1,600 meters.
Malherbe et al. (2012) conducted an observational in Right ventricular hypertrophy with heart failure (n=55). Elevation of 1,600 meters was evaluated on Development of progressive right-sided heart failure and right ventricular hypertrophy. Exposure to an elevation of 1,600 meters resulted in progressive right-sided heart failure and right ventricular hypertrophy in 55 Holstein heifers, consistent with brisket disease.