Why the study?
Do short periods of high pulmonary vascular pressures increase the capillary filtration coefficient in isolated dog lungs?
Population
Isolated dog lungs
Comparison
Short periods of high pulmonary vascular pressures vs Left atrial pressures < 30 cmH2O (controls)
Design
Preclinical
Follow-up
2 hours
Authors
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High left atrial pressure may transiently raise pulmonary filtration coefficient in isolated lungs; hypothesis-generating and leaves open human relevance.
Do short periods of high pulmonary vascular pressures increase the capillary filtration coefficient in isolated dog lungs?
High left atrial pressures transiently increase the filtration coefficient of pulmonary microvessels, suggesting a stretching of existing pores or opening of large pores.
Rippe et al. (1984) studied this question.
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