Key result
In anesthetized living dogs, the static compliance of the pulmonary venous system at a normal left atrial pressure of 10 mmHg was determined to be 0.227 ml × mmHg-1 × kg-1.
Population
Anesthetized living dogs
Comparison
Volume loading with dextran vs Control state
Design
Preclinical
Authors
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Does not inform clinical left atrial pressure management; leaves open translation of canine compliance models to humans.
This study established an exponential pressure-volume relationship for the pulmonary venous system in living dogs, providing a formula to calculate static compliance that aligns with indirect measurements in humans.
Hirakawa et al. (1987) studied this question. Volume loading with dextran vs. Control state was evaluated on Static compliance of the pulmonary venous system. In anesthetized living dogs, the static compliance of the pulmonary venous system at a normal left atrial pressure of 10 mmHg was determined to be 0.227 ml × mmHg-1 × kg-1.
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