Key result
The Stentys Xposition S Self-Apposing stent shows good clinical results and reduces malapposition compared to traditional balloon-expandable stents, though large randomized trials are lacking.
Why the study?
Challenging settings limit optimal PCI results, prompting a review of available literature on the Stentys Xposition S Self-Apposing stent compared with traditional balloon-expandable stents.
Does the Stentys Xposition S self-apposing stent improve procedural outcomes and reduce malapposition compared to traditional balloon-expandable stents in patients with coronary artery disease?
Does the Stentys Xposition S self-apposing stent improve procedural outcomes and reduce malapposition compared to traditional balloon-expandable stents in patients with coronary artery disease?
The Stentys Xposition S self-apposing stent may be a useful alternative to traditional stents in complex coronary lesions, but requires validation in large randomized trials.
Answers are grounded in this paper and cite their sources.
Self-apposing sirolimus-eluting stents may aid complex PCI; leaves open confirmation of clinical benefit in randomized trials.
Percutaneous coronary interventions are the primary revascularization strategy for the vast majority of patients with coronary artery disease. Nevertheless, challenging settings still limit optimal results, especially in case of significant tapering, bifurcations or primary angioplasty in ST-segment elevation myocardial infarction. Stentys® Self-Apposing® stent was designed to improve strut apposition to the vessel wall and to adapt to difficult targets. The Xposition S is a sirolimus-eluting stent with a novel delivery system, to improve accurate positioning. Several studies compared the device with traditional balloon-expandable stents, showing better results in terms of malapposition reduction and a noninferiority in relation to procedural outcomes. Available data show good clinical results, but a direct comparison with balloon-expandable stents from large randomized trials is still lacking. Thus, the Stentys Xposition S can be an alternative to traditional stents in dedicated scenarios, but strong evidence from large randomized trials is needed to derive stronger recommendations.
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Pellegrini et al. (2019) conducted a review in Coronary artery disease. Stentys Xposition S Self-Apposing stent vs. Traditional balloon-expandable stents was evaluated. The Stentys Xposition S Self-Apposing stent shows good clinical results and reduces malapposition compared to traditional balloon-expandable stents, though large randomized trials are lacking.
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