Key result
Heart transplant recipients had reduced LV global longitudinal strain early post-transplant compared to healthy controls (-17.7 vs -20.7; P=0.02), which progressively normalized by 2 years.
Why the study?
How do left and right ventricular global longitudinal strain evolve over the first 2 years after heart transplantation?
Cohort (n=56)
How do left and right ventricular global longitudinal strain evolve over the first 2 years after heart transplantation?
Absolute Event Rate: -17.7% vs -20.7%
p-value: p=0.02
Left and right ventricular global longitudinal strain are initially reduced after heart transplantation but progressively normalize over 1 to 2 years.
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Serial monitoring may guide post-HT surveillance; leaves open need for larger studies to define normative trajectories.
Palomero et al. (2016) conducted a cohort in Heart transplantation (n=56). Heart transplantation vs. Healthy volunteers was evaluated on LV global longitudinal strain (LV GLS) early post-HT (p=0.02). Heart transplant recipients had reduced LV global longitudinal strain early post-transplant compared to healthy controls (-17.7 vs -20.7; P=0.02), which progressively normalized by 2 years.
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