Why the study?
Does tidal volume variation influence the predictive value of Delta%VTI(Ao) and Delta%Pp for fluid responsiveness in mechanically ventilated critically ill patients?
Population
21 mechanically ventilated critically ill patients
Comparison
Intravascular volume expansion by hydroxyethyl… vs Before intravascular volume expansion and at…
Design
Cohort, Tidal volume (Vt) was randomly varied below and above its basal value
Authors
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Delta%VTI(Ao) may provide more consistent fluid responsiveness prediction across tidal volumes than Delta%Pp; extends observational data but requires prospective validation before practice change.
Does tidal volume variation influence the predictive value of Delta%VTI(Ao) and Delta%Pp for fluid responsiveness in mechanically ventilated critically ill patients?
Delta%VTI(Ao) and Delta%Pp are good predictors of fluid responsiveness in mechanically ventilated patients, though they respond differently to changes in tidal volume.
Charron et al. (2006) studied this question.
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