Key result
Hypertensive rheumatoid arthritis was associated with higher arterial stiffness index and common carotid intima-media thickness compared to hypertensive non-rheumatoid arthritis patients.
Why the study?
Does rheumatoid arthritis increase ambulatory arterial stiffness index and carotid intima-media thickness in hypertensive patients?
Cross-Sectional (n=94)
Does rheumatoid arthritis increase ambulatory arterial stiffness index and carotid intima-media thickness in hypertensive patients?
Hypertensive patients with rheumatoid arthritis have more pronounced subclinical atherosclerosis compared to hypertensive patients without rheumatoid arthritis.
Hypertensive RA patients may warrant closer vascular surveillance; cross-sectional data leaves open independent RA effects on atherosclerosis.
AIM: Rheumatoid arthritis is associated with accelerated atherosclerosis. However, little is known about preclinical atherosclerosis in hypertensive rheumatoid arthritis patients. In this cross-sectional study we assessed the expression of preclinical atherosclerosis in hypertensive rheumatoid arthritis patients in comparison with matched hypertensive non-rheumatoid arthritis patients. METHODS: The study included 52 hypertensive rheumatoid arthritis patients and 42 hypertensive non-rheumatoid arthritis patients. The patients were extensively examined clinically and laboratory tested. The expression of preclinical atherosclerosis was estimated by assessing ambulatory arterial stiffness index and common carotid intima-media thickness. RESULTS: Arterial stiffness index and common carotid intima-media thickness were higher in hypertensive rheumatoid arthritis patients than in hypertensive non-rheumatoid arthritis patients. There was no correlation between arterial stiffness index and common carotid intima-media thickness with markers of inflammation and disease activity in hypertensive rheumatoid arthritis patients. CONCLUSION: The expression of subclinical atherosclerosis is more pronounced in hypertensive rheumatoid arthritis than in hypertensive non- rheumatoid arthritis patients.
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Mitrović et al. (2015) conducted a cross-sectional in Hypertensive rheumatoid arthritis (n=94). Rheumatoid arthritis vs. Non-rheumatoid arthritis was evaluated on Ambulatory arterial stiffness index and common carotid intima-media thickness. Hypertensive rheumatoid arthritis was associated with higher arterial stiffness index and common carotid intima-media thickness compared to hypertensive non-rheumatoid arthritis patients.
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