Why the study?
Does the Rida Quick rotavirus/adenovirus Combi rapid immunochromatographic test accurately detect rotavirus and adenovirus compared to PCR in children with acute diarrhea?
Population
238 children with acute diarrhea in Ghana, mean age 10 months (range: 15 days to 11 years).
Comparison
Rida Quick rotavirus/adenovirus Combi rapid… vs Nested PCR for rotavirus and adenovirus
Design
Cross-sectional
Authors
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Supports ICT for rotavirus screening in resource-limited settings; leaves open adenovirus reliability and requires prospective validation.
Does the Rida Quick rotavirus/adenovirus Combi rapid immunochromatographic test accurately detect rotavirus and adenovirus compared to PCR in children with acute diarrhea?
The rapid immunochromatographic test is a practical and sufficiently reliable tool for detecting rotavirus, but not adenovirus, in resource-poor field settings.
Weitzel et al. (2007) studied this question.
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