Why the study?
Does low-dose acetylsalicylic acid prevent thrombovascular accidents in low-risk anaemic haemodialysis patients during initial treatment with recombinant human erythropoietin?
Population
137 anaemic haemodialysis patients without previous thrombovascular accidents or known increased risk for…
Comparison
Acetylsalicylic acid 30 mg daily vs Placebo
Design
RCT, double-blind
Follow-up
Correction of haematocrit plus 6 months
Authors
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Low-dose aspirin should not be used for thromboprophylaxis in low-risk hemodialysis patients starting erythropoietin; confirms lack of benefit in this RCT.
Does low-dose acetylsalicylic acid prevent thrombovascular accidents in low-risk anaemic haemodialysis patients during initial treatment with recombinant human erythropoietin?
Low-dose aspirin (30 mg daily) does not prevent thrombovascular accidents in low-risk hemodialysis patients starting erythropoietin therapy, although it prevents the erythropoietin-induced reduction in bleeding time.
Kooistra et al. (1994) studied this question.
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