Why the study?
Does high aerobic capacity reduce susceptibility to ischemia-reperfusion-mediated ventricular tachyarrhythmias in a rat model?
Population
Conscious rats selectively bred for high aerobic capacity (HCR, n=11) and low-capacity runners (LCR, n=7)
Comparison
High aerobic capacity subjected to 3 min of… vs Low aerobic capacity subjected to the same…
Design
Preclinical
Authors
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High aerobic capacity may protect against ischemia-reperfusion arrhythmias in rats; leaves open human translation and clinical relevance.
Does high aerobic capacity reduce susceptibility to ischemia-reperfusion-mediated ventricular tachyarrhythmias in a rat model?
Rats selectively bred for high aerobic capacity demonstrate a significantly reduced susceptibility to ischemia-reperfusion-mediated ventricular tachyarrhythmias compared to low-capacity runners.
Lujan et al. (2006) studied this question.