Why the study?
Does a reduced number of lyophilized plasma samples provide reliable ISI calibration for point-of-care PT monitors compared to standard WHO guidelines?
Population
Plasma samples from patients receiving coumarin, healthy subjects, and artificially depleted plasma samples
Comparison
Calibration using reduced numbers of European… vs Standard World Health Organization guidelines…
Design
Other
Authors
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May reduce calibration burden for POC PT monitors; leaves open prospective validation against WHO standards.
Does a reduced number of lyophilized plasma samples provide reliable ISI calibration for point-of-care PT monitors compared to standard WHO guidelines?
ISI calibration of point-of-care PT monitors can be simplified using significantly fewer lyophilized plasma samples than currently recommended by WHO guidelines.
Keown et al. (2003) studied this question.
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