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Six patients with peculiar angioblastic lesions associated with lymphoid infiltrates and a tissue eosinophilia are described. In 2 of the cases the newly formed vessels are apparently of arterial origin. The lesions which are solitary or multiple present as tumor-like swellings in the subcutaneous tissue of the head and neck. In addition, one patient had multiple cutaneous lesions distributed over the trunk and extremities. A significant blood eosinophilia was present in 2 cases. The disease is benign, but in its active phase may be mistakenly diagnosed as angiosarcoma. The lesions apparently respond to therapy with adrenocorticosteroids and to irradiation. Spontaneous remissions also occur.
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Reed et al. (1972) studied this question.
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