Why the study?
Does beta-adrenergic blockade with propranolol or CIBA 39,089-Ba induce or aggravate heart failure in patients with organic heart disease?
Does beta-adrenergic blockade with propranolol or CIBA 39,089-Ba induce or aggravate heart failure in patients with organic heart disease?
The text highlights the controversial risk of inducing or aggravating heart failure with beta-blockade therapy in patients with organic heart disease.
Supports caution with beta-blockade in organic heart disease; leaves open whether modern agents modify HF risk.
The danger of inducing or aggravating heart failure by beta-blockade remains a matter of con- troversy Whereas this risk has been considered as relatively small and acceptable by This risk undoubtedly represents an important drawback to this kind of therapy.
No takes yet. Share an insight, caveat, or question.
Grandjean et al. (1968) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: