November 1, 1993European Heart Journal
Family history as an independent risk factor for ischaemic heart disease in a low incidence area (Galicia, Spain)
Why the study?
Does a positive family history of CHD independently increase the risk of CHD in a low incidence area?
Population
212 individuals in a low incidence area, comprising 106 hospital cases of coronary heart disease and 106…
Comparison
Positive family history of coronary heart disease vs Negative family history of coronary heart disease
Design
Case-control
Authors
Discussion
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Member takes
Implication
Supports family history assessment for CHD risk in low-incidence areas; leaves open prospective validation before guiding practice.
Structured PICO
Does a positive family history of CHD independently increase the risk of CHD in a low incidence area?
P
Population
212 individuals in a low incidence area (Galicia, Spain), comprising 106 hospital cases of coronary heart disease (85 males, 21 females) and 106 hospital controls individually matched for sex, age, and place of residence (rural-urban).
I
Intervention
Positive family history of coronary heart disease (CHD)
C
Comparator
Negative family history of coronary heart disease (CHD)
O
Outcome
Presence of coronary heart disease (CHD)hard clinical
A positive family history of CHD is a strong, independent risk factor for ischemic heart disease, increasing the odds of CHD nearly five-fold even in a low-incidence population.
Cite This Study
Castro-Beiras et al. (1993) studied this question.