Population
Anesthetized dogs (skeletal muscle including gastrocnemius, splenius, latissimus dorsi, and masseter)
Comparison
Activation of sympathetic cholinergic… vs Resting levels and metabolic vasodilatation
Design
Preclinical
Authors
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Distinguishes neural from metabolic capillary recruitment in muscle; leaves open translation to human physiology.
The findings suggest that metabolic vasodilatation opens precapillary sphincters to increase capillary surface area, whereas sympathetic vasodilator nerves do not directly influence the exchange surface area.
Bolme et al. (1970) studied this question.
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