Population
Human erythrocytes (in vitro protein study)
Design
Preclinical
Authors
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May inform experimental models of sarcomere assembly; leaves open relevance to human cardiac disease.
Tropomodulin is identified as a novel tropomyosin-binding protein that regulates tropomyosin-actin interactions by binding to the end of tropomyosin and preventing its head-to-tail self-association.
Velia M. Fowler (1990) studied this question.