Why the study?
Does pindolol compared to propranolol affect renal function in patients with mild to moderate hypertension?
Population
14 subjects with mild to moderate hypertension
Comparison
Pindolol administered orally in equipotent… vs Propranolol administered orally in equipotent…
Design
Other, open
Authors
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Both beta-blockers appear to preserve renal function in mild hypertension; leaves open whether pindolol's lesser renin suppression confers advantage.
Does pindolol compared to propranolol affect renal function in patients with mild to moderate hypertension?
In patients with mild to moderate hypertension, both pindolol and propranolol maintain glomerular filtration rate and effective renal plasma flow without significant changes.
Pasternack et al. (1982) studied this question.