Why the study?
Does alprenolol reduce blood pressure and alter renal plasma flow or glomerular filtration rate in patients with essential hypertension?
Population
25 patients with essential hypertension, divided into two groups: 10 patients with mild hypertension under…
Comparison
Alprenolol treatment for one month vs Baseline (before treatment)
Design
Cohort
Follow-up
one month
Authors
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Supports differential BP response by age without renal compromise; hypothesis-generating and should not yet change practice.
Does alprenolol reduce blood pressure and alter renal plasma flow or glomerular filtration rate in patients with essential hypertension?
Alprenolol effectively lowers blood pressure without compromising renal plasma flow or glomerular filtration rate, with more pronounced antihypertensive effects in younger patients with mild hypertension.
E. B. Pedersen (1975) studied this question.
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