Why the study?
Does chronic hibernating myocardium undergo apoptosis and cellular degeneration, or is it an adaptive mechanism of cellular dedifferentiation?
Population
Patients with chronic hibernating myocardium
Design
Review
Authors
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May not yet alter revascularization timing in hibernating myocardium; leaves cellular mechanism debate unresolved for prospective trials.
Does chronic hibernating myocardium undergo apoptosis and cellular degeneration, or is it an adaptive mechanism of cellular dedifferentiation?
This review highlights the ongoing debate regarding the underlying cellular mechanisms of hibernating myocardium and its implications for the timing of revascularization.
G Dispersyn (2000) studied this question.