Key result
Augmented volume removal therapy reduced the intercept systolic BP and increased the rate of rise in systolic BP over the interdialytic interval, resulting in a reduced pulse pressure.
Why the study?
Does augmented volume removal therapy alter ambulatory blood pressure patterns in hypertensive hemodialysis patients?
Population
145 hypertensive hemodialysis patients from a randomized controlled trial, and an observational cohort of 37…
Design
Cohort
Follow-up
8 weeks (RCT cohort) and 6 months (observational cohort)
Authors
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May lower pulse pressure in hypertensive hemodialysis; hypothesis-generating, RCTs needed before practice change.
RCT (n=145)
Does augmented volume removal therapy alter ambulatory blood pressure patterns in hypertensive hemodialysis patients?
Augmented volume removal therapy in hemodialysis patients alters the ambulatory blood pressure pattern by reducing intercept systolic BP and pulse pressure, which may have implications for survival.
Rajiv Agarwal (2009) conducted an RCT in Hypertensive hemodialysis (n=145). Augmented volume removal therapy was evaluated on Ambulatory blood pressure patterns (intercept and slope of systolic BP). Augmented volume removal therapy reduced the intercept systolic BP and increased the rate of rise in systolic BP over the interdialytic interval, resulting in a reduced pulse pressure.
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