Why the study?
The study was conducted to examine the joint association of healthy lifestyles and statin use with all-cause and cardiovascular mortality in high-risk individuals, and to evaluate survival benefits by life expectancy.
Does the combination of statin use and a very healthy lifestyle reduce all-cause and cardiovascular mortality in individuals at high CVD risk?
Population
265,209 participants aged 35-75 years at high CVD risk in China
Comparison
Joint categories of healthy lifestyle (very healthy, healthy, unhealthy) and statin use
Design
Nationwide population-based cohort study
Follow-up
Median 3.6 years
Authors
Loading...
Supports combined statin-lifestyle strategies in high-risk adults; leaves open whether RCTs confirm additive survival gains.
Does the combination of statin use and a very healthy lifestyle reduce all-cause and cardiovascular mortality in individuals at high CVD risk?
The combination of statin therapy and multiple healthy lifestyle behaviors provides the largest survival benefits and lowest mortality risk in individuals at high cardiovascular risk.
Peng et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: