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January 31, 2012BMC Cardiovascular DisordersOpen Access

Metabolic syndrome was present in 67.9% by IDF criteria and 64.9% by NHLBI/AHA criteria, with an overall agreement of 81.5% (Kappa 0.59, p < 0.001).

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Why the study?

Does the NHLBI/AHA definition of metabolic syndrome identify a different cardiovascular risk profile compared to the IDF definition in patients with symptomatic carotid disease?

Population

644 consecutive patients with symptomatic carotid disease, referred to a vascular surgery clinic in…

Comparison

Diagnosis of metabolic syndrome using NHLBI/AHA… vs Diagnosis of metabolic syndrome using IDF criteria

Design

Cross-sectional

Authors

MMMiloš MaksimovićHVHristina VlajinacDRDjordje Radak

Discussion

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Member takes

Overview

Moderate agreement between IDF and NHLBI/AHA criteria in carotid disease; leaves open which better stratifies cardiovascular risk.

Structured PICO

Does the NHLBI/AHA definition of metabolic syndrome identify a different cardiovascular risk profile compared to the IDF definition in patients with symptomatic carotid disease?

P
Population
644 consecutive patients with symptomatic carotid disease (symptoms of cerebral ischemia and carotid stenosis ≥50% according to NASCET criteria), referred to a vascular surgery clinic in Belgrade, Serbia.
I
Intervention
Diagnosis of metabolic syndrome using NHLBI/AHA criteria
C
Comparator
Diagnosis of metabolic syndrome using IDF criteria
O
Outcome
Agreement between NHLBI/AHA and IDF definitions of metabolic syndrome and frequency of cardiovascular risk factors

In patients with symptomatic carotid disease, the NHLBI/AHA criteria may be more suitable for diagnosing metabolic syndrome than IDF criteria, as the IDF's strict central obesity requirement misses some patients with other significant cardiovascular risk factors.

Limitations

  • Cross-sectional design
  • Lack of follow-up to test the prognostic value of the definitions

Cite This Study

Maksimović et al. (2012) studied this question.

synapsesocial.com/papers/6a7cc1d9c2129568296ee19bhttps://doi.org/10.1186/1471-2261-12-2
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