Why the study?
Does the use of different thromboplastin sensitivities affect the reliability of INR for monitoring warfarin therapy?
Population
79 patients attending an anticoagulation clinic at a university hospital
Design
Cohort
Authors
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INR reliability may vary by thromboplastin sensitivity; leaves standardization unresolved and warrants high-sensitivity reagent evaluation.
Does the use of different thromboplastin sensitivities affect the reliability of INR for monitoring warfarin therapy?
Low-sensitivity thromboplastins may yield erroneously high INRs in the upper therapeutic range, highlighting the need for high-sensitivity thromboplastins for accurate warfarin monitoring.
Dzung The Le (1994) studied this question.
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