What question did this study set out to answer?

To review the evolving clinical utility of ethanol infusion as a primary, salvage, or adjunctive ablative strategy for managing complex and refractory cardiac arrhythmias.

June 7, 2015Current Opinion in CardiologyOpen Access

Ethanol for the treatment of cardiac arrhythmias

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Why the study?

Does ethanol infusion improve outcomes in patients with refractory cardiac arrhythmias?

Key Points

To review the evolving clinical utility of ethanol infusion as a primary, salvage, or adjunctive ablative strategy for managing complex and refractory cardiac arrhythmias.
Evaluated historical and contemporary clinical applications of intracoronary arterial ethanol infusion for drug-refractory ventricular tachycardia.
Assessed recent techniques utilizing retrograde ethanol delivery through cardiac venous systems, including the vein of Marshall and coronary veins.
Intracoronary arterial ethanol infusion effectively eliminates deep-seated myocardial arrhythmic foci that are inaccessible to standard endocardial or epicardial radiofrequency ablation.
Venous-route deliveries, such as vein of Marshall ethanol infusion for atrial fibrillation and coronary venous infusion for ventricular tachycardia, reduce arterial instrumentation risks while augmenting catheter ablation efficacy.

Structured PICO

Does ethanol infusion improve outcomes in patients with refractory cardiac arrhythmias?

Population

Patients with cardiac arrhythmias, specifically drug-refractory ventricular tachycardia or atrial fibrillation

Intervention

Ethanol infusion (intracoronary arterial or cardiac venous systems such as the vein of Marshall)

Ethanol infusion remains a useful bail-out or adjunctive technique for treating refractory cardiac arrhythmias when conventional radiofrequency ablation fails.

Discussion

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Implication

May be considered as bail-out for refractory arrhythmias; leaves open need for RCTs to confirm efficacy.

Cite This Study

Schürmann et al. (2015) studied this question.

synapsesocial.com/papers/6a7cea160487f0b2ef9291f5 https://doi.org/10.1097/hco.0000000000000183

Topics

Ventricular arrhythmias

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Ethanol for the treatment of cardiac arrhythmias

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Ethanol for the treatment of cardiac arrhythmias

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

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