Why the study?
Does varying the concentration of intracoronary ethanol ablation affect ventricular function, arrhythmogenesis, and lesion size in a swine model?
Does varying the concentration of intracoronary ethanol ablation affect ventricular function, arrhythmogenesis, and lesion size in a swine model?
In a swine model, intracoronary ethanol concentrations ≥50% create larger ventricular lesions but cause greater LV impairment and arrhythmogenesis.
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Higher ethanol concentrations may increase ablation risks in swine; leaves open optimal dosing for human translation.
Haines et al. (1994) studied this question.
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